Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.

Editors-in-Chief

  • Rocky S Tuan, University of Pittsburgh School of Medicine
  • Timothy O'Brien, National University of Ireland, Galway

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Articles

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  • Image attributed to: Lee et al Stem Cell Research & Therapy NSC transplantation

    Immune escape in neural stem cell transplantation

    Maintaining CD70 expression may enable continued immune escape in neural stem cell (NSC) transplantation as interaction between CD70 on NSCs and CD27 on T cells initiates NSC-induced CD4+ T cell apoptosis.

    Stem Cell Research & Therapy 2013, 4:56
  • Image attributed to: dental pulp-derived stem cells in collagen scaffold

    Collagen scaffolds in regenerative medicine

    Dental pulp- and amniotic fluid-derived stem cells seeded into collagen scaffolds repair large cranial bone defects in a rat model and are involved in vascularization of the implant.

    Stem Cell Research & Therapy 2013, 4:53
  • Image attributed to: osteogenic potential of tissue engineered constructs

    Increasing osteogenesis in tissue engineering

    Copolymer scaffolds can be prevascularized with endothelial cells (EC) and mesenchymal stem cells (MSC); seeding of MSC with or without EC increases the osteogenic potential of tissue-engineered constructs.

    Stem Cell Research & Therapy 2013, 4:52

  • Monitoring neurodegeneration in diabetes

    Adult neural stem cells extracted from the olfactory bulb of diabetic rats can be cultured in vitro and show similar gene expression profiles to hippocampal neural stem cells during diabetes progression.

    Stem Cell Research & Therapy 2013, 4:51
  • Image attributed to: Wang et al

    Vasculogenesis in first-trimester pregnancy

    Human first-trimester decidua side population cells can differentiate into endothelial cells and form tube-like structures in vitro and may induce vasculogenesis in vivo in the ischemic limb nude mouse model.

    Stem Cell Research & Therapy 2013, 4:50
  • Image attributed to: placenta wikipedia public domain

    Placental tissue as an HPC source

    Higher expression levels of the hematopoiesis-related genes SALL4 and BMI-1 in placental tissue compared with umbilical cord blood suggest it might be a good source for expansion of hematopoietic progenitor cells (HPCs). 

    Stem Cell Research & Therapy 2013, 4:49
  • Image attributed to: aMSC quimby et al stem cell res ther 2013

    Treating feline chronic kidney disease

    Intravenous administration of cryopreserved allogeneic adipose-derived mesenchymal stem cells in cats with chronic kidney disease resulted in significant adverse effects and no clinical improvement.

    Stem Cell Research & Therapy 2013, 4:48
  • Image attributed to: Cancer definition

    The importance of timing

    Celia Gomes comments on research showing human mesenchymal stem cells (MSCs) slow tumor growth in established murine tumors, whereas MSC administration appears to increase growth in newly formed tumors.

    Stem Cell Research & Therapy 2013, 4:42
  • Image attributed to: hMSC from Keramidas et al Stem Cell Res Ther

    Stem cell therapy in cancer

    Injection of human mesenchymal stem cells into established tumors in mice slowed tumor growth, and this effect appeared to be due to changes in tumor angiogenesis.

    Stem Cell Research & Therapy 2013, 4:41
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Stem Cell Immunology

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Stem Cell Research & Therapy Volume 4 Issue 2

The complete issue of Stem Cell Research & Therapy Volume 4 Issue 2 is now available.

Latest free review

The following review has recently become free to access:

Review

Orthopaedic applications of nanoparticle-based stem cell therapies

Ian Wimpenny, Hareklea Markides, Alicia J El Haj

Stem Cell Research & Therapy 2012, 3:13
(19 April 2012)

Abstract | Full text | PDF | PubMed

Quotes

Timothy 0'Brien
"Stem cells have enormous potential for alleviating suffering for many diseases which currently have no effective therapy. The field has progressed to the clinic and it is important that this pathway is underpinned by excellent science and rigorous standards of clinical research. The journal provides an important avenue of publication in translational aspects of stem cell therapy spanning preclinical studies, clinical research and commercialization."

Prof. Timothy O'Brien,
Editor-in-Chief
Stem Cell Research & Therapy


Rocky S Tuan
"The study of stem cells is one of the most exciting areas of contemporary biomedical research. We believe that Stem Cell Research & Therapy will act as a highly active forum for both basic and translational research into stem cell biology and therapies. Specifically, by developing this forum for cutting edge research, we hope that Stem Cell Research & Therapy will play a significant role in bringing together the critical information to synergize stem cell science with stem cell therapies."

Dr. Rocky S Tuan
Editor-in-Chief
Stem Cell Research & Therapy

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ISSN: 1757-6512