Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes open access research articles of outstanding quality. Stem Cell Research & Therapy has a special emphasis on basic, translational, and clinical research into stem cell therapeutics, including animal models, and clinical trials.
Editors-in-Chief
- Rocky Tuan, University of Pittsburgh School of Medicine
- Timothy O'Brien, National University of Ireland, Galway
Articles
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Stem Cell Research & Therapy 2010, 1:22Novel approach for treating radiation-induced complications
Treatment with granulocyte colony-stimulating factor-mobilized CD34+ hematopoietic stem cells from bone marrow into peripheral blood could promote tissue reparation after acute liver injury by radiation in mice.
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Stem Cell Research & Therapy 2010, 1:20Stem cell contribution to reconstituted mammary ducts
Microenvironmental cues of the mammary fat pad cause amniotic fluid stem cells to form a supportive stroma for extending ductal epithelium, but don’t incorporate or differentiate into ductal epithelial cells.
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Stem Cell Research & Therapy 2010, 1:18Medium induces mesenchymal stem cell differentiation
Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation towards nucleus pulposus-like phenotype with characteristics of the developing intervertebral disc (IVD), suggesting notochordal cells as a promising target for IVD repair.
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Stem Cell Research & Therapy 2010, 1:15Mesenchymal stem cell immunosuppressive properties
Findings that immunosuppressive properties are probably shared by all stromal cells including fibroblasts and stem cells isolated from exfoliated deciduous teeth may have clinical implications.
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Stem Cell Research & Therapy 2010, 1:13Understanding cancerous stem cells
Cancerous stem cells, the result of changes in signaling pathways involved in stem cell survival and proliferation, show resistance to cancer therapies, and understanding their unique characteristics is key to targeting therapies towards them.
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Stem Cell Research & Therapy 2010, 1:12Solving the pluripotent stem cell puzzle
Pirity and Dinnyes discuss the recent finding that T box gene 3 can improve the quality of induced pluripotent stem cells (iPSCs) and the potential implication this may have on improving iPSC technology.
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Stem Cell Research & Therapy 2010, 1:14Gene expression varies during stem cell development
Migration-related genes are progressively upregulated in a murine Lineage-Sca-1+c-Kit+ cell population during their transition to the bone marrow microenvironment.
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Stem Cell Research & Therapy 2010, 1:11Multipotency regulation of mesenchymal progenitor cells
Activin A expression acts as a functional marker for multipotent mesenchymal progenitor cells, allowing for identification of the more desirable cell types for use in regenerative medicine.
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Latest issue
The complete issue of Stem Cell Research & Therapy Volume 1 Issue 2 is now available.
Latest review
All reviews, commentaries and reports published in Stem Cell Research & Therapy are free to read. See below for the latest free review.
Clinical and preclinical translation of cell-based therapies using
adipose tissue-derived cells 
Jeffrey M Gimble, Farshid Guilak, Bruce A Bunnell
Stem Cell Research & Therapy 2010, 1:19Quotes
"Stem cells have enormous potential for alleviating suffering for many diseases which currently have no effective therapy. The field has progressed to the clinic and it is important that this pathway is underpinned by excellent science and rigorous standards of clinical research. The journal provides an important avenue of publication in translational aspects of stem cell therapy spanning preclinical studies, clinical research and commercialization."
Prof. Timothy O'Brien,
Editor-in-Chief
Stem Cell Research & Therapy
"The study of stem cells is one of the most exciting areas of contemporary biomedical research. We believe that Stem Cell Research & Therapy will act as a highly active forum for both basic and translational research into stem cell biology and therapies. Specifically, by developing this forum for cutting edge research, we hope that Stem Cell Research & Therapy will play a significant role in bringing together the critical information to synergize stem cell science with stem cell therapies."
Dr. Rocky S Tuan
Editor-in-Chief
Stem Cell Research & Therapy
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ISSN: 1757-6512