Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.


  • Rocky S Tuan, University of Pittsburgh School of Medicine
  • Timothy O'Brien, National University of Ireland, Galway


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  • Motor neuron derivation and application

    Corti and colleagues review the experimental approaches for differentiating human embryonic stem cells and human induced pluripotent stem cells towards functional motor neurons, and summarise their potential clinical applications.

    Stem Cell Research & Therapy 2014, 5:87
  • Unique tenogenic progenitor properties

    Peritenon-derived and tendon proper progenitors respond uniquely in a regenerative model, highlighting the synergistic potential of including these progenitor populations in restorative tendon engineering strategies.

    Stem Cell Research & Therapy 2014, 5:86
  • Diabetic ASCs have impaired angiogenic potential

    Diabetic mesenchymal stem cells derived from adipose tissue (ASCs) have impaired functional and therapeutic capacity due to their ability to establish a vascular network in vitro and in vivo.

    Stem Cell Research & Therapy 2014, 5:79
  • Image attributed to: Gasparotto et al Stem Cell Res Ther osteogenic differentiation

    Snake venom-derived scaffold candidate

    A new fibrin sealant derived from snake venom shows potential as a three-dimensional scaffold for mesenchymal stem cells, maintaining cell survival without promoting differentiation.

    Stem Cell Research & Therapy 2014, 5:78
  • Image attributed to: Byrne, Stem Cell Res Ther excerpt from fig 1

    Stem cell therapy for neurodegeneration

    James Byrne comments on recent research demonstrating that genetically modified neural stem cells can deliver disease-modifying therapeutic proteins throughout the brains of rodent models of Alzheimer’s disease.

    Stem Cell Research & Therapy 2014, 5:72
  • Image attributed to: Balducci et al Stem Cell Res Ther hASCs

    Immortalization of adipose-derived stromal cells

    Immortalized human adipose-derived stromal cells maintain most of their original mesenchymal features, in particular the capability to produce significant amounts of angiogenic factors, with potential advantages for laboratory research and regenerative medicine.

    Stem Cell Research & Therapy 2014, 5:63
  • Image attributed to: Bellayr et al Stem Cell Res Ther microarray analysis

    Markers of cellular aging in cultured MSCs

    Specific gene markers which distinguish aging multipotent stromal cells (MSCs) grown in culture are identified through gene expression profiling using microarray technology.

    Stem Cell Research & Therapy 2014, 5:59
  • Image attributed to: Stem cells iStockPhoto

    WJ-MSC transplantation in diabetes

    Treatment with Wharton’s jelly mesenchymal stem cells (WJ-MSC) can improve metabolic control and beta cell function in patients with type 2 diabetes mellitus.

    Stem Cell Research & Therapy 2014, 5:57
  • Image attributed to: Dhamodoran et al Stem Cell Res Ther ocular stem cell sources

    Cell-based therapy in ophthalmology

    Debashish Das and colleagues review the stem cell populations of the eye and their respective functions in cell-based therapy and regenerative medicine in ophthalmology.

    Stem Cell Research & Therapy 2014, 5:56
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Latest issue

Stem Cell Research & Therapy Volume 5 Issue 3

The complete issue of Stem Cell Research & Therapy Volume 5 Issue 3 is now available.

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Latest free review

The following review has recently become free to access:


Production of mesenchymal stromal/stem cells according to good manufacturing practices: a review

Luc Sensebé, Mélanie Gadelorge, Sandrine Fleury-Cappellesso

Stem Cell Research & Therapy 2013, 4:66
(7 June 2013)


Timothy 0'Brien
"Stem cells have enormous potential for alleviating suffering for many diseases which currently have no effective therapy. The field has progressed to the clinic and it is important that this pathway is underpinned by excellent science and rigorous standards of clinical research. The journal provides an important avenue of publication in translational aspects of stem cell therapy spanning preclinical studies, clinical research and commercialization."

Prof. Timothy O'Brien,
Stem Cell Research & Therapy

Rocky S Tuan
"The study of stem cells is one of the most exciting areas of contemporary biomedical research. We believe that Stem Cell Research & Therapy will act as a highly active forum for both basic and translational research into stem cell biology and therapies. Specifically, by developing this forum for cutting edge research, we hope that Stem Cell Research & Therapy will play a significant role in bringing together the critical information to synergize stem cell science with stem cell therapies."

Dr. Rocky S Tuan
Stem Cell Research & Therapy

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ISSN: 1757-6512