Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.


  • Rocky S Tuan, University of Pittsburgh School of Medicine
  • Timothy O'Brien, National University of Ireland, Galway


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  • Image attributed to: Hucklenbroich et al, 2014

    Aromatic turmerone induces neural stem cell proliferation

    Aromatic turmerone increased the number of neural stem cells in cell culture and adult rat brains in vivo, suggesting it would make a promising drug candidate for neural regeneration.

    Stem Cell Research & Therapy 2014, 5:100
  • Image attributed to: Llucia-Valldeperas et al 2014

    Physiological conditioning by electric field stimulation

    The cardioregeneration capability of cardiomyocyte progenitor cells is improved by electric field stimulation; this could be used to modify cardiac progenitor cells towards a cardiogenic phenotype and incorporated into transdifferentiation protocols.

    Stem Cell Research & Therapy 2014, 5:93
  • Reparative activity of pericardial ADSCs

    Although phenotypically identical, pericardial adipose tissue-derived stromal cells (ADSCs) in comparison to subcutaneous ADSCs were shown to exhibit potent differentiation towards cardiomyocytes and induced significant structural repair in the injured heart.

    Stem Cell Research & Therapy 2014, 5:92
  • Motor neuron derivation and application

    Corti and colleagues review the experimental approaches for differentiating human embryonic stem cells and human induced pluripotent stem cells towards functional motor neurons, and summarise their potential clinical applications.

    Stem Cell Research & Therapy 2014, 5:87
  • Unique tenogenic progenitor properties

    Peritenon-derived and tendon proper progenitors respond uniquely in a regenerative model, highlighting the synergistic potential of including these progenitor populations in restorative tendon engineering strategies.

    Stem Cell Research & Therapy 2014, 5:86
  • Diabetic ASCs have impaired angiogenic potential

    Diabetic mesenchymal stem cells derived from adipose tissue (ASCs) have impaired functional and therapeutic capacity due to their ability to establish a vascular network in vitro and in vivo.

    Stem Cell Research & Therapy 2014, 5:79
  • Image attributed to: Gasparotto et al Stem Cell Res Ther osteogenic differentiation

    Snake venom-derived scaffold candidate

    A new fibrin sealant derived from snake venom shows potential as a three-dimensional scaffold for mesenchymal stem cells, maintaining cell survival without promoting differentiation.

    Stem Cell Research & Therapy 2014, 5:78
  • Image attributed to: Byrne, Stem Cell Res Ther excerpt from fig 1

    Stem cell therapy for neurodegeneration

    James Byrne comments on recent research demonstrating that genetically modified neural stem cells can deliver disease-modifying therapeutic proteins throughout the brains of rodent models of Alzheimer’s disease.

    Stem Cell Research & Therapy 2014, 5:72
Research Awards
Stem Cell Immunology
Physical influences in stem cells -- special series
StemCell Research clinical Applications
Stem Cell Research in Asia Pacific

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Stem Cell Research & Therapy Volume 5 Issue 5

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Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: from the genetic, epigenetic, and tissue modeling perspectives

Maggie Chow, Kenneth R Boheler, Ronald A Li

Stem Cell Research & Therapy 2013, 4:97 (14 August 2013)


Timothy 0'Brien
"Stem cells have enormous potential for alleviating suffering for many diseases which currently have no effective therapy. The field has progressed to the clinic and it is important that this pathway is underpinned by excellent science and rigorous standards of clinical research. The journal provides an important avenue of publication in translational aspects of stem cell therapy spanning preclinical studies, clinical research and commercialization."

Prof. Timothy O'Brien,
Stem Cell Research & Therapy

Rocky S Tuan
"The study of stem cells is one of the most exciting areas of contemporary biomedical research. We believe that Stem Cell Research & Therapy will act as a highly active forum for both basic and translational research into stem cell biology and therapies. Specifically, by developing this forum for cutting edge research, we hope that Stem Cell Research & Therapy will play a significant role in bringing together the critical information to synergize stem cell science with stem cell therapies."

Dr. Rocky S Tuan
Stem Cell Research & Therapy

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ISSN: 1757-6512