Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.


  • Rocky S Tuan, University of Pittsburgh School of Medicine
  • Timothy O'Brien, National University of Ireland, Galway


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  • Image attributed to: Stem cells iStockPhoto

    WJ-MSC transplantation in diabetes

    Treatment with Wharton’s jelly mesenchymal stem cells (WJ-MSC) can improve metabolic control and beta cell function in patients with type 2 diabetes mellitus. 

    Stem Cell Research & Therapy 2014, 5:57
  • Image attributed to: Dhamodoran et al Stem Cell Res Ther ocular stem cell sources

    Cell-based therapy in ophthalmology

    Debashish Das and colleagues review the stem cell populations of the eye and their respective functions in cell-based therapy and regenerative medicine in ophthalmology.

    Stem Cell Research & Therapy 2014, 5:56
  • Image attributed to: iStockPhoto xray of arm

    Stem cell therapy for bone repair

    Cynthia Coleman and colleagues review recent advances in the identification, isolation, and mechanism of action of mesenchymal stem cells in bone fracture repair, and discuss their clinical implications.

    Stem Cell Research & Therapy 2014, 5:51
  • Image attributed to: Maternal placental MSCs, Zhu et al Stem Cell Res Ther

    Differences in placental mesenchymal stem cells

    Fetal placental mesenchymal stem cells (MSCs) express higher levels of CD200 and hepatocyte growth factor compared with maternal placental MSCs, and show increased potential for promoting angiogenesis and immunosuppression. 

    Stem Cell Research & Therapy 2014, 5:48
  • Image attributed to: Nasopharynx, wikipedia, Gray's Anatomy, public domain

    Nasopharyngeal cancer stem-like cells

    Pingpin Wei et al. review recent studies on cancer-like stem cells in nasopharyngeal carcinoma, including their isolation, characterisation and therapeutic approaches.

    Stem Cell Research & Therapy 2014, 5:44
  • Image attributed to: Zhang et al Stem Cell Res Ther Oil Red O staining aged MSCs

    Aiding efficacy of aging stem cells

    Sherry Wang and Jun Ren comment on recent research showing that inhibition of IP6Ks turns on Akt signaling, decreases apoptosis, and modulates the paracrine profile in mesenchymal stem cells.

    Stem Cell Research & Therapy 2014, 5:43
  • Image attributed to: Rojas et al Stem Cell Res Ther, sheep lung diagram

    Adult stem cells for ARDS

    Administration of adult bone marrow-derived stem cells appears to improve lung function, inflammatory response and hemodynamic changes in a sheep model of acute respiratory distress syndrome (ARDS). 

    Stem Cell Research & Therapy 2014, 5:42
  • Image attributed to: Song et al Stem Cell Res Ther progerin expression

    Vasculopathy in progeria

    Mutant lamin A occurrence and high shear stress correlate with a reduction in the level of mechanotransduction proteins in smooth muscle cells which may contribute to development of vasculopathy in progeria syndrome.

    Stem Cell Research & Therapy 2014, 5:41
  • Image attributed to: Abbah et al Stem Cell Res Ther tendon engineering

    Stem cell carriers for tendon repair

    Dimitrios Zeugolis and colleagues discuss recent advances in stem cell carriers for tendon tissue engineering in preclinical models, including injectable carriers, tissue grafts and anisotropic scaffolds.

    Stem Cell Research & Therapy 2014, 5:38
Stem Cell Immunology
Physical influences in stem cells -- special series
StemCell Research clinical Applications
Stem Cell Research in Asia Pacific

Latest issue

Stem Cell Research & Therapy Volume 5 Issue 1

The complete issue of Stem Cell Research & Therapy Volume 5 Issue 1 is now available.

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Latest free review

The following review has recently become free to access:


Topological and electrical control of cardiac differentiation and assembly

Nimalan Thavandiran, Sara S Nunes, Yun Xiao, Milica Radisic

Stem Cell Research & Therapy 2013, 4:14
(14 February 2013)


Timothy 0'Brien
"Stem cells have enormous potential for alleviating suffering for many diseases which currently have no effective therapy. The field has progressed to the clinic and it is important that this pathway is underpinned by excellent science and rigorous standards of clinical research. The journal provides an important avenue of publication in translational aspects of stem cell therapy spanning preclinical studies, clinical research and commercialization."

Prof. Timothy O'Brien,
Stem Cell Research & Therapy

Rocky S Tuan
"The study of stem cells is one of the most exciting areas of contemporary biomedical research. We believe that Stem Cell Research & Therapy will act as a highly active forum for both basic and translational research into stem cell biology and therapies. Specifically, by developing this forum for cutting edge research, we hope that Stem Cell Research & Therapy will play a significant role in bringing together the critical information to synergize stem cell science with stem cell therapies."

Dr. Rocky S Tuan
Stem Cell Research & Therapy

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ISSN: 1757-6512