Table 1

Effect of G-CSF-mobilized CD34⁺ cells on murine liver function after irradiation

Mice

ALT (IU/L)

AST (IU/L)

ALB⁺/Y-chromosome⁺ cells

0 d

3 d

7 d

21 d

0 d

3 d

7 d

21 d

14 d

21 d

G1

37.9 ± 7.2

418.3 ± 49.8^†

228.3 ± 32.7*

78.3 ± 5.7*

31.1 ± 6.9

398.3 ± 42.8^†

256.3 ± 36.8*

89.2 ± 6.4*

_

+^#

G2

36.4 ± 6.7

434.5 ± 53.8

378.6 ± 51.2

169.3 ± 34.7

29.8 ± 6.3

402.5 ± 46.5

381.2 ± 50.9

209.5 ± 38.4

_

_

G3

38.4 ± 7.1

40.9 ± 6.1

38.3 ± 6.8

42.3 ± 6.7

30.7 ± 6.5

31.7 ± 6.4

30.8 ± 6.9

31.1 ± 6.5

_

_

Data are means ± SD (n = 10). *P < 0.05 compared with the G2 mice; †P > 0.05 compared with the G2 mice. #Human ALB⁺/Y chromosome⁺ hepatocyte-like cells in the liver of G1 mice. G-CSF, granulocyte colony-stimulating factor; ALB, albumin; ALT, alanine aminotransferase aspartate; AST, aspartate aminotransferase.

Li et al. Stem Cell Research & Therapy 2010 1:22   doi:10.1186/scrt22