Research
Fetal derived embryonic-like stem cells improve healing in a large animal flexor tendonitis model
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* Corresponding author: Alan J Nixon ajn1@cornell.edu
1 Department of Clinical Sciences, Comparative Orthopaedics Laboratory at Cornell University, Ithaca, NY, 14850 USA
2 Celavet, Inc., Celavie Biosciences, LLC, 2360 Eastman Ave, Suite 101, Oxnard, CA, 93030 USA
Stem Cell Research & Therapy 2011, 2:4 doi:10.1186/scrt45
Published: 27 January 2011Additional files
Additional File 1:
rt-PCR primer and probe sequences. Sequences (5' to 3') for forward and reverse primers and probes used in quantitative PCR. Sequences were selected from equine specific sequences published in GenBank.
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Additional File 2:
Gross morphology. Photographs of the superficial digital flexor tendon (SDFT) in cross-section at 17 cm distal to the accessory carpal bone (lateral is to the right) and of the palmar surface of the mid-metacarpal SDFT. A) fetal-derived Embryonic-like stem cell treated tendons and B) placebo control treated tendons. Asterisks mark proximolateral in images of the palmar surface.
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Additional File 3:
Gene expression and biochemical data. Selected gene expression and total collagen, proteoglycan and DNA content of fetal-derived embryonic-like stem cell versus placebo control treated tendon following collagenase induction of injury. There were no significant differences between either group for any parameter.
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