Stem Cell Research & Therapy | Volume 2 Issue 2

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	Volume 2 Issue 2
	Comment
	Commentary A zinc finger protein Zfp521 directs neural differentiation and beyond Sanbing Shen, Jin Pu, Bing Lang, Colin D McCaig Stem Cell Research & Therapy 2011, 2:20 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
	Commentary Acute myeloid leukemia: leukemia stem cells write a prognostic signature Emma J Gudgin, Brian JP Huntly Stem Cell Research & Therapy 2011, 2:21 (27 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Gudgin and Huntly comment on a recent article in which transcriptional dysregulation in acute myeloid leukemia (AML) stem cells are directly related with outcome in patient samples.
	Review
	Review Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment Jonathan Hoggatt, Louis M Pelus Stem Cell Research & Therapy 2011, 2:13 (14 March 2011) Abstract \| Full text \| PDF \| PubMed
	Review Mesenchymal stem cell-based therapies in regenerative medicine: applications in rheumatology Marie Maumus, David Guérit, Karine Toupet, Christian Jorgensen, Danièle Noël Stem Cell Research & Therapy 2011, 2:14 (18 March 2011) Abstract \| Full text \| PDF \| PubMed
	Review Neural tissue engineering using embryonic and induced pluripotent stem cells Stephanie M Willerth Stem Cell Research & Therapy 2011, 2:17 (15 April 2011) Abstract \| Full text \| PDF \| PubMed
	Review Epigenetic regulation of satellite cell activation during muscle regeneration F Jeffrey Dilworth, Alexandre Blais Stem Cell Research & Therapy 2011, 2:18 (19 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Therapeutic modulation of Polycomb group and Trithorax group protein activities in satellite cells, a population of adult muscle stem cells, could represent a viable approach for repairing damaged muscle in muscular dystrophy.
	Research
	Research Constitutive G_sactivation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice Edward C Hsiao, Trieu D Nguyen, Jennifer K Ng, Mark J Scott, Wei Chun Chang, Hengameh Zahed, Bruce R Conklin Stem Cell Research & Therapy 2011, 2:11 (4 March 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A modular system allows the rapid generation of tetracycline-regulated expression constructs for gene expression studies in embryonic stem cells and mice, and the rapid introduction of different combinations of promoters and expressed transgenes.
	Research Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia Lisa McGinley, Jill McMahon, Padraig Strappe, Frank Barry, Mary Murphy, Daniel O'Toole, Timothy O'Brien Stem Cell Research & Therapy 2011, 2:12 (7 March 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Mesenchymal stem cells (MSCs) can be efficiently transduced in vitro to express a variety of therapeutic genes using a lentiviral vector, with potential to improve the efficacy of MSC-based therapies.
	Research Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid Christopher D Krause, Lara S Izotova, Gwangwen Ren, Zeng-Rong Yuan, Yufang Shi, Chiann-Chyi Chen, Yacov Ron, Sidney Pestka Stem Cell Research & Therapy 2011, 2:15 (14 March 2011) Abstract \| Full text \| PDF \| PubMed
	Research Stimulation of Activin A/Nodal signaling is insufficient to induce definitive endoderm formation of cord blood-derived unrestricted somatic stem cells Caitlin E Filby, Robert Williamson, Peter van Kooy, Alice Pébay, Mirella Dottori, Ngaire J Elwood, Faten Zaibak Stem Cell Research & Therapy 2011, 2:16 (4 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Unlike human embryonic stem cells, stimulation of the Nodal signaling pathway with Activin A is insufficient to induce definitive endoderm formation from umbilical cord blood-derived unrestricted somatic stem cells (USSCs).
	Research Gene expression changes with differentiation of cord blood stem cells to respiratory epithelial cells: a preliminary observation Michael J Berger, Sharon R Minnerath, Sheryl D Adams, Barbara M Tigges, Stacey L Sprague, David H McKenna Jr Stem Cell Research & Therapy 2011, 2:19 (13 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Berger et al. present an account of the changes in gene expression that accompany the differentiation of human umbilical cord blood (UCB)-derived stem cells toward type II pneumocytes.