Therapeutic effects of low-dose hUCB-MSC administration on infarction volume in the ischemic animal model. (a) Brain slices were stained with TTC at seven days after 5 × 105 hUCB-MSC administration. The images show the lesion volume in hUCB-MSCs treated groups. (b) The data were collected from five animals per group and are presented as mean relative infarct volume ± SD. Statistically significant differences between the groups were determined by analysis of variance (*P < 0.05 compared with the PBS injected group intrathecally; #P < 0.05 compared with the hUCB-MSCs injected group intravenously).
Lim et al. Stem Cell Research & Therapy 2011 2:38 doi:10.1186/scrt79