Stem Cell Research & Therapy | Volume 3 Issue 1

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	Volume 3 Issue 1
	Comment
	Commentary When one cell is enough Rhodri Ceredig Stem Cell Research & Therapy 2012, 3:1 (13 January 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Rhodri Ceredig discusses a significant advance in our understanding of human hematopoiesis.
	Commentary Stem cell-based therapy for α₁-antitrypsin deficiency S Tamir Rashid, David A Lomas Stem Cell Research & Therapy 2012, 3:4 (9 February 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Bone marrow mononuclear cells and acute myocardial infarction Samer Arnous, Abdul Mozid, John Martin, Anthony Mathur Stem Cell Research & Therapy 2012, 3:2 (17 January 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The use of bone-marrow derived mononuclear cells in cardiac repair after acute myocardial infarction, a leading cause of death and disability, is reviewed by Anthony Mathur and colleagues.
	Review The therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms Sara Morando, Tiziana Vigo, Marianna Esposito, Simona Casazza, Giovanni Novi, Maria Principato, Roberto Furlan, Antonio Uccelli Stem Cell Research & Therapy 2012, 3:3 (26 January 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Many studies have demonstrated that mesenchymal stem cells are effective in the treatment of experimental autoimmune encephalomyelitis (EAE) and may have potential as a therapeutic option in multiple sclerosis.
	Review Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head Lars Rackwitz, Lars Eden, Stephan Reppenhagen, Johannes C Reichert, Franz Jakob, Heike Walles, Oliver Pullig, Rocky S Tuan, Maximilian Rudert, Ulrich Nöth Stem Cell Research & Therapy 2012, 3:7 (22 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Ulrich Noth and colleagues review regenerative medicine approaches to treating avascular necrosis of the femoral head, a debilitating disease often leading to osteoarthritis and eventually hip replacement in young adults.
	Research
	Research Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells Lei Wang, Ziyan Liu, Sivasai Balivada, Tej Shrestha, Stefan Bossmann, Marla Pyle, Loretta Pappan, Jishu Shi, Deryl Troyer Stem Cell Research & Therapy 2012, 3:5 (10 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Glioma cells that fail to self-renew in standard conditions can gain this ability after exposure to IL-1β and TGF-β suggesting targeting glioma stem cell-promoting cytokines may increase the efficacy of glioma therapies.
	Research Phenotypical and functional characteristics of mesenchymal stem cells from bone marrow: comparison of culture using different media supplemented with human platelet lysate or fetal bovine serum Nesrine Azouna, Faouzi Jenhani, Zohra Regaya, Lamia Berraeis, Tarek Othman, Elfi Ducrocq, Jorge Domenech Stem Cell Research & Therapy 2012, 3:6 (14 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Mesenchymal stem cells expanded in human platelet lysate supplemented media without fetal bovine serum (FBS) retain their phenotype and differentiation capacity, while an increased growth rate may allow for reduced culture time.