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Volume 3 Issue 3

Comment

Commentary   Subscription

Can a young muscle's stem cell secretome prolong our lives?

Karl JA McCullagh Stem Cell Research & Therapy 2012, 3:19 (28 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Karl McCullagh comments on recent findings that a population of muscle stem cells are able to prolong life in a mouse model of premature ageing.

Review

Review   Free

Strategies for enrichment and selection of stem cell-derived tissue precursors

Harold S Bernstein, William C Hyun Stem Cell Research & Therapy 2012, 3:17 (10 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Bernstein and Hyun review strategies used to direct tissue-specific differentiation of embryonic stem cells (ESCs), and methods for the identification and selection of tissue-specific precursors for scientific study and clinical use.

Review   Subscription Highly Accessed

Mesenchymal stem cell therapy for attenuation of scar formation during wound healing

Wesley M Jackson, Leon J Nesti, Rocky S Tuan Stem Cell Research & Therapy 2012, 3:20 (31 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Editor-in-Chief Rocky Tuan and colleagues review the use of mesenchymal stem cells (MSCs) to promote scar-less wound healing, including the mechanisms by which they can limit tissue fibrosis.

Research

Research   Open Access

The secretome of stem cells isolated from the adipose tissue and Wharton jelly acts differently on central nervous system derived cell populations

Carlos A Ribeiro, Joana S Fraga, Mário Grãos, Nuno M Neves, Rui L Reis, Jeffrey M Gimble, Nuno Sousa, António J Salgado Stem Cell Research & Therapy 2012, 3:18 (2 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The secretome of human umbilical cord perivascular cells (HUPVCs) and adipose tissue-derived stem cells differ, with HUPVC conditioned media able to promote neuronal survival and differentiation without exogenous supplement.

Research   Open Access

Characterization of lung stem cell niches in a mouse model of bleomycin-induced fibrosis

Ena Banerjee, William Henderson Stem Cell Research & Therapy 2012, 3:21 (29 May 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

Jagadeesh K Venkatesan, Myriam Ekici, Henning Madry, Gertrud Schmitt, Dieter Kohn, Magali Cucchiarini Stem Cell Research & Therapy 2012, 3:22 (28 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Transfer of SOX9 via replication-defective recombinant adeno-associated virus (rAAV) vector enhances the chondrogenic potential of human mesenchymal stem cells, with potential for future therapeutic applications to restore articular cartilage defects.


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