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Monitoring neurodegeneration in diabetes using adult neural stem cells derived from the olfactory bulb
Ryo Hidaka, Masanao Machida, Shin Fujimaki, Kazuyuki Terashima, Makoto Asashima, Tomoko Kuwabara Stem Cell Research & Therapy 2013, 4:51 (14 May 2013)
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Editor’s summary
Adult neural stem cells extracted from the olfactory bulb of diabetic rats can be cultured in vitro and show similar gene expression profiles to hippocampal neural stem cells during diabetes progression.
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Vasculogenesis of decidua side population cells of first-trimester pregnancy
Qiushi Wang, Licong Shen, Wei Huang, Yong Song, Li Xiao, Wenming Xu, Ying Liu Stem Cell Research & Therapy 2013, 4:50 (7 May 2013)
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Editor’s summary
Human first-trimester decidua side population cells can differentiate into endothelial cells and form tube-like structures in vitro and may induce vasculogenesis in vivo in the ischemic limb nude mouse model.
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Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia
Cheuk-Kwan Sun, Steve Leu, Jiunn-Jye Sheu, Tzu-Hsien Tsai, Hsin-Chin Sung, Yung-Lung Chen, Sheng-Ying Chung, Sheung-Fat Ko, Hsueh-Wen Chang, Hon-Kan Yip Stem Cell Research & Therapy 2013, 4:31 (21 March 2013)
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Identification of mouse colony-forming endothelial progenitor cells for postnatal neovascularization: a novel insight highlighted by new mouse colony-forming assay
Shizu Tsukada, Sang-Mo Kwon, Takenori Matsuda, Seok-Yun Jung, Jun-Hee Lee, Sang-Hun Lee, Haruchika Masuda, Takayuki Asahara Stem Cell Research & Therapy 2013, 4:20 (28 February 2013)
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Overexpression of Bcl-2 promotes survival and differentiation of neuroepithelial stem cells after transplantation into rat aganglionic colon
Wei Liu, Weiming Yue, Rongde Wu Stem Cell Research & Therapy 2013, 4:7 (16 January 2013)
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Editor’s summary
Genetically-modifying neural epithelial stem cells (NESCs) to over express the anti-apoptotic gene Bcl-2 enhances both their survival and neuronal differentiation on transplantation into aganglionic colon, potentially improving cell therapy for gastrointestinal disorders.
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Zebrafish erythropoiesis and the utility of fish as models of anemia
Kasem Kulkeaw, Daisuke Sugiyama Stem Cell Research & Therapy 2012, 3:55 (20 December 2012)
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Editor’s summary
As part of the Asia-Pacific series, Kulkeaw and Sugiyama review our understanding of erythropoiesis based on studies using zebrafish, and the utility of fish models in human anemia.
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Novel mechanism for mesenchymal stem cells in attenuating peritoneal adhesion: accumulating in the lung and secreting tumor necrosis factor α-stimulating gene-6
Nan Wang, Yeqing Shao, Yan Mei, Li Zhang, Qinggang Li, Diangeng Li, Suozhu Shi, Quan Hong, Hongli Lin, Xiangmei Chen Stem Cell Research & Therapy 2012, 3:51 (6 December 2012)
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Editor’s summary
Intravenously injected mesenchymal stem cells (MSCs) accumulate in the lung and reduce peritoneal adhesion by secreting TSG-6, however MSCs injected intraperitoneally are phagocytosed by splenic macrophages and fail to attenuate peritoneal adhesion.
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Induced pluripotent stem cell technology for disease modeling and drug screening with emphasis on lysosomal storage diseases
Hsiang-Po Huang, Ching-Yu Chuang, Hung-Chih Kuo Stem Cell Research & Therapy 2012, 3:34 (28 August 2012)
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Editor’s summary
Hung-Chih Kuo and colleagues review recent advances in the use of induced pluripotent stem cells (iPSCs) for disease modelling and drug screening in lysosomal storage diseases (LSDs).
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Human foreskin fibroblast produces interleukin-6 to support derivation and self-renewal of mouse embryonic stem cells
Yu Ma, Junjie Gu, Chunliang Li, Xiaoyuan Wei, Fan Tang, Guilai Shi, Jing Jiang, Ying Kuang, Jinsong Li, Zhugang Wang, Xin Xie, Ying Jin Stem Cell Research & Therapy 2012, 3:29 (31 July 2012)
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Editor’s summary
Human foreskin fibroblasts (HFF) produce interleukin-6 to support the derivation and maintenance of mouse embryonic stem cell (ESC) lines, providing a convenient, efficient and inexpensive ESC culture system.
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