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Articles

Physical influences on stem cells

Edited by: Prof Gordana Vunjak-Novakovic

Submissions to this series are open! If you would like your research manuscript to be considered for publication alongside the commissioned reviews in the series please submit online, mentioning the physical influences series in your covering letter.

Collection published: 31 October 2012

Last updated: 3 April 2013

		Review Micropatterning of cells reveals chiral morphogenesis Leo Q Wan, Kacey Ronaldson, Mark Guirguis, Gordana Vunjak-Novakovic Stem Cell Research & Therapy 2013, 4:24 (3 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Leo Wan and colleagues discuss left-right asymmetry and possible roles of cell chirality in stem cell differentiation, including the importance of in vitro cell chirality model systems in understanding chiral morphogenesis in development.
		Review Topological and electrical control of cardiac differentiation and assembly Nimalan Thavandiran, Sara S Nunes, Yun Xiao, Milica Radisic Stem Cell Research & Therapy 2013, 4:14 (14 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Milica Radisic and colleagues review the use of engineered surface topology and electrical control in directing the cardiac differentiation of stem cells and the production of engineered heart tissue.
		Review Mechanical control of tissue-engineered bone Ben P Hung, Daphne L Hutton, Warren L Grayson Stem Cell Research & Therapy 2013, 4:10 (31 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Warren Grayson and colleagues review the use of mechanical forces to enhance osteogenesis in bone tissue engineering, based on knowledge obtained from mechanobiology studies of native bone.
		Review Vascular tissue engineering: biodegradable scaffold platforms to promote angiogenesis Janna V Serbo, Sharon Gerecht Stem Cell Research & Therapy 2013, 4:8 (24 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary As part of the Physical influences on stem cells series, Serbo and Gerecht discuss the use of biodegradable scaffolds to control vascular network formation and promote angiogenesis in damaged tissue.
		Review Biophysical regulation of stem cell behavior within the niche Anthony Conway, David V Schaffer Stem Cell Research & Therapy 2012, 3:50 (14 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Conway and Schaffer review the biophysical aspects of the microenvironment which are involved in the regulation of stem cell development and fate, including mechanoregulation and the spatial organization of cues.
		Review Hydrodynamic modulation of pluripotent stem cells Krista M Fridley, Melissa A Kinney, Todd C McDevitt Stem Cell Research & Therapy 2012, 3:45 (20 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Todd McDevitt and colleagues discuss the use of hydrodynamic culture systems for the expansion and differentiation of pluripotent stem cells, and their role in developing high throughput cell generation systems.
		Review Dynamics of branched tissue assembly Sriram Manivannan, Celeste M Nelson Stem Cell Research & Therapy 2012, 3:42 (31 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Manivannan and Nelson discuss two examples that highlight the dynamic nature of tissue assembly: formation of the trachea in drosophila and branching of the ducts in the mouse mammary gland.
		Review Force-dependent cell signaling in stem cell differentiation Evelyn KF Yim, Michael P Sheetz Stem Cell Research & Therapy 2012, 3:41 (31 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Yim and Sheetz introduce the components of the mechanotransduction machinery and review recent developments regarding their role in directing stem cell differentiation and cell fate determination.

		Review Micropatterning of cells reveals chiral morphogenesis Leo Q Wan, Kacey Ronaldson, Mark Guirguis, Gordana Vunjak-Novakovic Stem Cell Research & Therapy 2013, 4:24 (3 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Leo Wan and colleagues discuss left-right asymmetry and possible roles of cell chirality in stem cell differentiation, including the importance of in vitro cell chirality model systems in understanding chiral morphogenesis in development.
		Review Topological and electrical control of cardiac differentiation and assembly Nimalan Thavandiran, Sara S Nunes, Yun Xiao, Milica Radisic Stem Cell Research & Therapy 2013, 4:14 (14 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Milica Radisic and colleagues review the use of engineered surface topology and electrical control in directing the cardiac differentiation of stem cells and the production of engineered heart tissue.
		Review Mechanical control of tissue-engineered bone Ben P Hung, Daphne L Hutton, Warren L Grayson Stem Cell Research & Therapy 2013, 4:10 (31 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Warren Grayson and colleagues review the use of mechanical forces to enhance osteogenesis in bone tissue engineering, based on knowledge obtained from mechanobiology studies of native bone.
		Review Vascular tissue engineering: biodegradable scaffold platforms to promote angiogenesis Janna V Serbo, Sharon Gerecht Stem Cell Research & Therapy 2013, 4:8 (24 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary As part of the Physical influences on stem cells series, Serbo and Gerecht discuss the use of biodegradable scaffolds to control vascular network formation and promote angiogenesis in damaged tissue.
		Review Biophysical regulation of stem cell behavior within the niche Anthony Conway, David V Schaffer Stem Cell Research & Therapy 2012, 3:50 (14 December 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Conway and Schaffer review the biophysical aspects of the microenvironment which are involved in the regulation of stem cell development and fate, including mechanoregulation and the spatial organization of cues.
		Review Hydrodynamic modulation of pluripotent stem cells Krista M Fridley, Melissa A Kinney, Todd C McDevitt Stem Cell Research & Therapy 2012, 3:45 (20 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Todd McDevitt and colleagues discuss the use of hydrodynamic culture systems for the expansion and differentiation of pluripotent stem cells, and their role in developing high throughput cell generation systems.
		Review Dynamics of branched tissue assembly Sriram Manivannan, Celeste M Nelson Stem Cell Research & Therapy 2012, 3:42 (31 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Manivannan and Nelson discuss two examples that highlight the dynamic nature of tissue assembly: formation of the trachea in drosophila and branching of the ducts in the mouse mammary gland.
		Review Force-dependent cell signaling in stem cell differentiation Evelyn KF Yim, Michael P Sheetz Stem Cell Research & Therapy 2012, 3:41 (31 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Yim and Sheetz introduce the components of the mechanotransduction machinery and review recent developments regarding their role in directing stem cell differentiation and cell fate determination.